Limonoids and Quassinoids, the bitter principles of Rutales. (Photos: Limonin, Lemon and Simarouba(Laxmi-taru) We all are familiar with , though unknowingly, these compounds. The delayed bitterness of the juices from various Citrus spp., which were considered as the culprits lowering the juice quality, is due to limonoids. The word “Limonoids’ is derived from “limonin” the first bitter principle isolated from lemon. Limonoid aglycones that cause bitterness in numerous citrus fruits are converted into tasteless limonoid glucosides during fruit maturation. More than 50 limonoid aglycones and glucosides have been identified from various Citrus species. Over 300 limonoids have been isolated to date and about one-third are generated from neem (Azadirachta indica) and Chinaberry (Melia azedarach). These compounds are characteristically present in the order “Rutales” consisting of Rutaceae, Meliaceae, Simaroubaceae and Cneoraceae (Daniel, 2009). ...
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